ICLAC交叉污染细胞系数据库

ICLAC最新公布的交叉污染（错误鉴定）细胞系数据库(Misidentified Cell Lines Database)，大家赶紧对比看看自己培养的细胞是否在列。

目前ICLAC总共列出了552个被交叉污染（错误鉴定）细胞系。其中509个被错误认定的细胞系，且目前找不到最初正确的细胞系库存。另43个被错误认定的细胞系，但目前有找到正确的细胞系库存。

若您目前培养的细胞属于509个错误认定的细胞，请尽快停止项目。若细胞属于表2中43个细胞系，可先进行细胞STR鉴定，看是否有污染。如被污染了，需找到拥有正确细胞系库存的可靠供应商购买。

数据库中有列出154个不同的污染源，其中HeLa是最大的污染源（129个细胞系被证实HeLa污染），依次是T-24(21个细胞系被证实T-24污染) 和 M14 (18个细胞系被证实M14污染)。

以下列出了部分被HeLa、HT-29、HepG2、DU-145等污染的细胞系。

Misidentified CellLine	Claimed Cell Type	Misidentified Cell   Line, Cellosaurus AC	Contaminating Cell   Line
2563 (MAC-21)	Lung carcinoma	CVCL_M629	HeLa
ACC2	adenoid cystic	CVCL_6872	HeLa
ACC3	adenoid cystic	CVCL_6873	HeLa
ACCM	adenoid cystic	CVCL_6874	HeLa
ADLC-5M2	Lung carcinoma	CVCL_8169	HeLa
AKI	Melanoma	CVCL_8170	HeLa
AO	Amnion	CVCL_D631	HeLa
ARO	Thyroid, anaplastic	CVCL_0144	HT-29
ARO81-1	Thyroid, anaplastic	CVCL_0144	HT-29
AV3	Amnion	CVCL_1904	HeLa
BCC1/KMC	Basal cell carcinoma	CVCL_A033	HeLa
BM-1604	Prostate carcinoma	CVCL_1968	DU-145
BrCA 5	Breast carcinoma	CVCL_D280	HeLa
BT-B	Bladder carcinoma	CVCL_1858	HeLa
C16 (MRC-5   derivative)	Lung cells, fetal	CVCL_2322	HeLa
CaOV	Ovarian carcinoma	CVCL_M091	HeLa
CaVe	Gastric carcinoma	CVCL_8444	HeLa
Chang   liver	Liver, normal hepatic	CVCL_0238	HeLa
Clone 1-5c-4	Conjunctiva	CVCL_2260	HeLa
CMP	Rectal	CVCL_D297	HeLa
CMPII C2	Rectal	CVCL_L115	HeLa
CNE-1	Nasal pharynx,	CVCL_6888	HeLa
CNE-2	Nasal pharynx,	CVCL_6889	HeLa
D18T	Synovial cell	CVCL_8669	HeLa
D98/AH	Not specified	CVCL_U961	HeLa
D98/AH2   Clone B	Not specified	CVCL_2884	HeLa
DAPT	Astrocytoma, piloid	CVCL_D279	HeLa
Det30A	Breast carcinoma,	CVCL_8674	HeLa
Detroit-6 (Det6)	Sternal marrow cells	CVCL_2436	HeLa
Detroit-98	Sternal marrow cells	CVCL_8188	HeLa
Detroit 98/AG	Sternal marrow cells	CVCL_8189	HeLa
Detroit   98/AH-2	Sternal marrow cells	CVCL_8190	HeLa
Detroit 98/AH-R	Sternal marrow cells	CVCL_8191	HeLa
Detroit   98s	Sternal marrow cells	CVCL_8192	HeLa
EB33	Prostate carcinoma	CVCL_8344	HeLa
ED27	Chorionic villus	CVCL_8345	HeLa
ElCo	Breast carcinoma	CVCL_8686	HeLa
EPLC3-2M1	Lung carcinoma	CVCL_8193	HeLa
EPLC-65	Lung carcinoma	CVCL_8194	HeLa
ESP1	Lymphoma, Burkitt	CVCL_8351	HeLa
EUE	Subcutis, fetal	CVCL_7262	HeLa
F255A4	Not specified	CVCL_8688	HeLa
FL	Amnion	CVCL_1905	HeLa
G-11   (HBT-3 derivative)	Breast carcinoma	CVCL_U962	HeLa
Girardi heart	Heart, normal cells	CVCL_2254	HeLa
H-494	Prostate carcinoma	CVCL_7669	HeLa
H7D7A and   derivatives	Liver, normal cells	CVCL_1T06	HepG2
H7D7B   and derivatives	Liver, normal cells	CVCL_1T07	HepG2
H7D7C and   derivatives	Liver, normal cells	CVCL_1T08	HepG2
H7D7D   and derivatives	Liver, normal cells	CVCL_1T09	HepG2
HBT-3	Breast carcinoma	CVCL_D281	HeLa
HBT-39b	Breast carcinoma	CVCL_J652	HeLa
HBT-E (HBT-3 clone)	Breast carcinoma	CVCL_M746	HeLa
HCE	Cervical carcinoma	CVCL_M619	HeLa
HEK	Kidney, embryonic renal cells	CVCL_M624	HeLa
HEK/HRV   (HEK derivative)	Kidney, transformed embryonic   renal cells	CVCL_M625	HeLa
HEp-2 (H.Ep.-2)	Laryngeal carcinoma	CVCL_1906	HeLa
Hep-2C	Laryngeal carcinoma	CVCL_2940	HeLa
Hep2 (Clone 2B)	Laryngeal carcinoma	CVCL_2817	HeLa
HES	Endometrium	CVCL_W635	HeLa
HL111783	Lung carcinoma	CVCL_8231	HeLa
HMV-1	Melanoma	CVCL_8233	HeLa
HPC-36M (HPC-36   derivative)	Prostate carcinoma	CVCL_8446	HeLa
HSG	Salivary gland,	CVCL_2517	HeLa
HSG-AZA1	Salivary gland,	CVCL_A047	HeLa
HSG-AZA3	Salivary gland,	CVCL_A048	HeLa
HSGc-C5	Oral carcinoma	CVCL_2951	HeLa
HSY	Salivary gland, parotid	CVCL_B032	HeLa
HuKo39	Kidney, normal renal	CVCL_8283	HeLa
HuL-1	Liver, hepatocellular	CVCL_8357	HeLa
Hut	Not specified	CVCL_M861	HeLa
IMC-2	Maxillary carcinoma	CVCL_8245	HeLa
IMC-3	Maxillary carcinoma	CVCL_8246	HeLa
IMC-4	Maxillary     carcinoma	CVCL_8247	HeLa
Intestine 407   (Int-407, HEI)	Intestinal cells	CVCL_1907	HeLa
J-111	Leukemia, acute	CVCL_2965	HeLa
J96	Leukemia	CVCL_3990	HeLa
JHC	Placenta	CVCL_M093	HeLa
JHT (JHC derivative)	Placenta	CVCL_M620	HeLa
JHU028	Oral squamous cell	CVCL_5992	A549
JTC-17	Skin	CVCL_8362	HeLa
JTC-3	Not specified	CVCL_A034	HeLa
KAK1	Thyroid, follicular	CVCL_6301	HT-29
KAT10	Thyroid, papillary	CVCL_6302	HT-29
KAT4	Thyroid, anaplastic	CVCL_6304	HT-29
KAT5	Thyroid, papillary	CVCL_0370	HT-29
KAT50	Thyroid, differentiated	CVCL_6305	HT-29
KAT7	Thyroid, benign	CVCL_6306	HT-29
KB	Oral carcinoma	CVCL_0372	HeLa
KB-3-1	Oral carcinoma	CVCL_2088	HeLa
KB-V1	Oral carcinoma	CVCL_2089	HeLa
KM20	Colon carcinoma	CVCL_L095	HT-29
KM20L2 (KM20   derivative)	Colon carcinoma	CVCL_D889	HT-29
KP-P1	Prostate carcinoma	CVCL_D283	HeLa
KU7	Bladder carcinoma	CVCL_4714	HeLa
L-132	Lung cells, embryonic	CVCL_1908	HeLa
L-41 (J96   derivative)	Leukemia, bone	CVCL_7170	HeLa
LC5 (L-132 derivative)	Lung cells, embryonic	CVCL_5G52	HeLa
LC5-HIV (L-132   derivative)	Lung cells, embryonic	CVCL_5G53	HeLa
LED-Ti	Cervical carcinoma	CVCL_8438	HeLa
LU	Lung cells, fetal	CVCL_M631	HeLa
LU 106	Lung cells, embryonic	CVCL_8892	HeLa
M10T	Synovial cell	CVCL_M094	HeLa
MA-160	Prostate adenoma	CVCL_8261	HeLa
MaTu	Breast carcinoma	CVCL_5328	HeLa
MC-4000	Breast carcinoma	CVCL_5331	HeLa
MRO87-1	Thyroid, follicular	CVCL_6310	HT-29
MS	Kidney, normal renal	CVCL_4243	HeLa
lines with same	Breast carcinoma	CVCL_0441	HeLa
MV522	Lung carcinoma	CVCL_7204	HT-29
NCTC 2544	Skin epithelium	CVCL_0461	HeLa
NCTC 3075	Not specified	CVCL_8156	HeLa
ND-1	Prostate carcinoma	CVCL_4781	DU-145
OE	Endometrium	CVCL_J350	HeLa
OF	Not specified	CVCL_M621	HeLa
OS 187	Sarcoma	CVCL_1R50	HCT-15
OST	Sarcoma	CVCL_8399	HeLa
OV-1063	Ovarian carcinoma	CVCL_4366	DU-145
PC-93	Prostate carcinoma	CVCL_4888	HeLa
RO-D81-1	Thyroid, medullary	CVCL_M779	HT-29
RPMI-4788	Colon carcinoma	CVCL_0U46	HeLa
SA4	Sarcoma	CVCL_8910	HeLa
SBC-2	Bladder carcinoma	CVCL_1677	HeLa
SBC-7	Bladder carcinoma	CVCL_1680	HeLa
SH-2	Breast carcinoma	CVCL_M622	HeLa
SH-3	Breast carcinoma	CVCL_M383	HeLa
SQ-5	Lung carcinoma	CVCL_8273	HeLa
T-1	Kidney, normal renal	CVCL_M858	HeLa
T1	Neural stem cell	CVCL_1U15	HeLa
T-9	Lung cells,	CVCL_M092	HeLa
TuWi	Kidney, Wilms' tumor	CVCL_8275	HeLa
WiDr	Colon carcinoma	CVCL_2760	HT-29
WISH	Amnion, normal cells	CVCL_1909	HeLa
Wong-Kilbourne	Conjunctiva	CVCL_2764	HeLa
WRL 68	Liver, embryonic cells	CVCL_0581	HeLa